Series of multivalent α-l-fucoside containing glycoclusters and variously decorated l-fucosides were synthesized to find potential inhibitors of fucose-specific lectins and study the structure-binding affinity relationships.Tri- and tetravalent fucoclusters were built using copper-mediated azide-alkyne click chemistry.Series of fucoside monome
Abstract Background Colorectal cancer (CRC) is one of the most common malignancies of the digestive system, which causes severe financial burden worldwide.However, the specific mechanisms involved in CRC are still unclear.Methods To identify the significant genes and pathways involved in the initiation and progression of CRC, the microarray dataset
Economically feasible strategies for year-round feed supply to dairy cattle are needed to improve feed resource availability, milk yield and household income for the smallholder dairy farming systems wella color touch 77 45 that predominate in the rural Eastern and Central African region.Currently, Napier grass (Pennisetum purpureum) is the major f
This article explores the pervasiveness of employee absenteeism in the South African Police Service (SAPS) at the station level and the factors that contribute to it.Employee absenteeism is a critical problem for most organisations and the SAPS is no exception.While measures have been put in place to curb this problem in the SAPS by the here police